Author: TheCBD.place
Basic noobie guide for CBD dosages
CBD Oil Dosage – General Advice to Assess How Much CBD to Take
Even with the wave of states legalizing medical marijuana, many physicians are still reluctant to prescribe cannabinoids because they are not sure what dosages to prescribe. After all, most medical schools never cover CBD Cannabidiol in their pharmacology courses. Medical scientists are just now developing dosing schedules for medical marijuana, medicinal hemp and their extracts, including CBD.
CBD-rich hemp oil comes in various concentrations and forms, including liquid hemp oil, hemp oil as a thick paste, oil in capsules, sublingual tincture drops or sprays, salves for topical use, edibles as in candy or gum and CBD vapor from vaporizers similar to e-cigarettes.
Everyone Is Different
What you will find on this page is meant to be a guideline, a starting point of reference. The fact remains that everyone is in a different place and will react differently to their CBD dosage. As serving size or dosage of CBD differs for each person, it is best to start small and gradually increase until you experience the desired result.
CBD Brands Confusing Dosage
CBD oil brands create a lot of confusion for consumers because they all have different standards. Many of them recommend way too much as a “serving” and others recommend too little. Because of this lack of standard during our review of individual CBD products,
It is also recommended that you try increasing dosage every 3-4 weeks by 25mg until symptom relief. And to decrease amount of CBD with any worsening of symptoms.
CBD Oil Dosing
Concentrations vary between preparations, ranging from 1 mg per dose to hundreds of milligrams. This makes it easy for consumers to get the dosages they need in a form they find easy to use.
CBD Dosages
Mayo Clinic suggests CBD dosages on scientific research, publications, traditional use, or expert opinion. Cannabinoid dosages and duration of treatment depend largely on the disease.
How Much CBD Oil Should I Take?
To increase appetite in cancer patients: 2.5 milligrams of THC by mouth with or without 1 mg of CBD for six weeks
To treat chronic pain: 2.5-20 mg CBD by mouth for an average of 25 days.
To treat epilepsy: 200-300 mg of CBD by mouth daily.
To treat movement problems associated with Huntington’s disease: 10 mg per kilogram of CBD by mouth daily for six weeks.
To treat sleep disorders: 40-160 mg CBD by mouth.
To treat multiple sclerosis symptoms: Cannabis plant extracts containing 2.5-120 milligrams of a THC-CBD combination by mouth daily for 2-15 weeks. A mouth spray might contain 2.7 milligrams of THC and 2.5 milligrams of CBD at doses of 2.5-120 milligram for up to eight weeks. Patients typically use eight sprays within any three hours, with a maximum of 48 sprays in any 24-hour period.
To treat schizophrenia: 40-1,280 mg CBD by mouth daily.
To treat glaucoma: a single CBD dose of 20-40 mg under the tongue. Doses greater than 40 mg may actually increase eye pressure.
According to CannLabs, the nation’s top full-service testing lab for cannabis products, there is no established lethal CBD dose. Consumers should read product inserts carefully to ensure they are taking the right amount of CBD, and talk to the prescribing physician about any questions or concerns.
Still Have Questions? Get info from other users on reddit!
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Your Ultimate Guide to CBD dabbing
If you are a soccer fan, you may associate dabbing with an idiotic celebration of doing the rounds. As it happens, ‘dabbing’ is also the term used to describe the consumption of extremely potent CBD. Companies such as CBDistillery sell CBD concentrates in wax, shatter, butter, or powder form. They are usually 99% pure which makes them a lot more effective, and expensive, than CBD oils and edibles.
While dabbing is also performed with THC products, this comprehensive guide tells you more about the types of CBD concentrates on the market, the creation of concentrates, the right dabbing tools to use, and also helpful information on the correct dabbing technique.
Why Dabbing?
The entire dabbing process will seem alien to you at first, but you’ll soon get used to it. It is technically classified as “the flash vaporization” of CBD concentrates when it is applied to a hot surface and then inhaled. You ‘dab’ using concentrates which are a lot more potent than the CBD you get from oils and edibles.
It is normal for a CBD isolate to contain 99% of the cannabinoid, and while it is expensive, users swear by its impact. To be honest, we wouldn’t recommend dabbing to CBD newcomers, though – you will get so used to the rapid relief that you won’t accept CBD oils or edibles ever again!
Types of Concentrates on the Market
While there are various types of concentrates available, high-quality versions all contain huge doses of CBD.
- Wax: While this concentrate has a relatively firm texture, it breaks easily.
- Butter: This substance is soft and easy to manipulate.
- Shatter: This is a brittle option which ‘shatters’ easily as per the name. The best quality shatter tends to be golden yellow. Shatter with a darker color tends to have a lot of impurities. It is typically the most potent option.
- Crystalline: This is a fancy term for powder. Its main advantage is that it is easy to work with as an ingredient.
How is CBD Concentrate Made?
While we can’t speak for every product on the market, we can tell you how CBD concentrate should be made. The best products are extracted from non-GMO hemp via supercritical CO2 extraction. The concentrate that is produced should include the cannabinoids, fatty acids and other plant materials naturally found in hemp.
The next step involves purifying the CBD hemp oil using a proprietary process for removing excess waxes and plant materials. The result is a 99% pure CBD isolate in one of the forms mentioned above. Reputable companies will include third-party lab testing results on their websites, and the top firms have isolate that is between 99.7% and 99.9% pure. They also utilize ISO/IEC 17025:2005 accredited testing labs, which results in CBD that is free from toxins, heavy metals, mildew, mold, fungus and other impurities.
CBD Dabs – An Introduction to concentrates
We’ll cover how they are made, the different types, and the difference between THC dabs and CBD dabs. The main difference being the content of cannabinoids CBD and THC.
CBD Dabs – Types of concentrates
There are several types of concentrates but all of them are purified extractions of cannabis resin contained within the trichomes. CBD Dabs differ in that they contain higher levels of CBD than is normally found in high THC concentrates.
Budder/Wax/Shatter
Budder has a soft caramel like texture and is quite flexible and easy to manipulate.
Waxes are slightly firmer than butter and may break if handled too rough
Shatter is much harder and quite brittle compared to waxes. they are generally a clear golden yellow to amber color. the darker the shatter the more impurities there are in the material.
Oil
Hash oil or phoenix tears are a liquid concentrate and is one of the oldest concentrates in the industry
Hash
Hash or hashish is pressed kief or trichomes as they are known scientifically. Hash is one of the oldest concentrates and dates back several centuries where it was made by hand in india as charas.
Kief
kief is the loose powder form of trichomes. It can be found at the bottom of any 3 or 4 piece grinder purified by a screen. press this powder and you get hash.
CBD Dabs – How are they made
There are two main methods of creating cannabis concentrates, solvent-based extraction and non-solvent extraction. In solvent-based extraction, chemical solvents such as butane, propane, carbon dioxide (CO2) and alcohol are used to separate resin glands containing the psychoactive compound THC from the cannabis flower. In non-solvent extractions, water, temperatureand pressure are the predominant factors.
Solvent-based extractions utilize chemical solvents to strip cannabis flowers of their highly potent resin glands. Because chemical solvents are often highly flammable, professional extractors use what are called “closed-loop” systems to ensure that there is no airborne chemical exposure during the process, therefore eliminating any risk for fire, over-pressurization or explosion. This is why concentrate production should only be conducted by licensed professionals. It is extremely dangerous and illegal to perform solvent-based extractions at home, so leave the process to the professionals!
CBD Dabs – The Tools
Essentially, dabbing is the flash vaporization of cannabis concentrates once applied to a hot surface and inhaled. These concentrates are a lot more potent than marijuana flowers, so a little bit goes a long way.
Dabbing technology is evolving, but the traditional setup includes the following items (keep in mind that the appearance of each tool may vary slightly depending on its design):
- A cannabis extract. Any of the above listed concentrates like budder, wax, or shatter. Do not use alcohol based extracts for dabbing as trace amounts of alcohol may be present and is combustible.
- A water pipe. You can take the glass bowl pieces out and replace them with dabbing attachments to turn your pipe into a dab rig.
- A nail. Find a nail that fits your water pipe’s gauge. Some are made of ceramic and quartz, but titanium is the most commonly used type.
- A dome. This is the glass hood placed around the nail. “Dome-less” nails (see below) don’t need a glass globe, but standard nails need something to trap the vapor before it’s inhaled.
- A torch. Mini-torches used for crème brulee will do the job, but some choose to upgrade to larger propane-fueled torches that heat nails faster. New flame-less methods of dabbing are becoming available, but most people still use the torch method due to the low cost investment.
- A dabber. This is the glass, metal, or ceramic tool used to apply a dab.
What Are Dabbing Tools?
Although dabbing technology is long from being in its infancy, there is still plenty of room for improvement. Nonetheless, there are several dabbing tools available to help you consume your CBD isolate in the most efficient manner possible. What we will say is this: If you are only picking one option, choose a tool capable of being versatile when it comes to handling concentrates of differing consistencies.
The important thing to remember is that you will be vaporizing your concentrates.
- Dabbing Rig: This is a modified water pipe that has a glass joint designed to hold a nail instead of a connector (as you would have on a bubbler or bong). With this tool, you heat up the nail and place the concentrate on it to cause vaporization. There are various sizes available, so decide if you want a mini-rig or a larger one that sits on a coffee table.
- Nail: You can purchase a quartz or titanium nail. Aficionados tend to choose quartz because it provides better flavor. Also, with titanium, there is a danger of oxidation at high temperatures and these nails can degrade when used improperly.
- Carb Cap Dabber: The purpose of this tool is to place the concentrate on the hot nail safely. If you have dry concentrate, choose a wide dabber as it does a better job of scooping. A Carb Cap also enables you to dab at a slightly lower temperature. This is vital because at the reduced temperature, you get more of the terpenes which are lost at higher temperatures.
- Dab Rag/Mat: This handy piece of equipment acts as a stand for the rig. Without it, there’s a good chance that your table will get coated in sticky residue. It is best to purchase an easily washable rag or mat. You can also use the rag to remove the mess made from dabbing.
- Torch: How else are you going to heat up the nail? Remember to purchase a butane refill as your torch will be empty when you purchase it.
- Electronic Nail: This is a must for concentrate lovers as it is an adjustable and constant heat source which means there is no need for a torch. The downside? E-Nails are expensive and can cost up to $300.
What is the Correct Dabbing Technique?
Once all your equipment is in place, turn on the torch and make sure the flame is hitting the nail. Don’t make the mistake of overheating the nail, though – a lot of people prefer to heat it until it turns red hot, but this isn’t necessary. In fact, too much heat can reduce the quality of CBD.
When the nail is hot enough, switch off the torch and place the glass dome over the nail. If you use quartz nails, allow them to cool for 45 seconds; for titanium nails, the waiting period is just 10 seconds.
Use your dabber to grab the correct amount of CBD concentrate and add it directly to the nail inside the dome. Inhale the vapor slowly and rotate the dabber tip on the nail to avoid wasting oil that could be stuck to the dabber. Exhale, enjoy, and repeat until satisfied.
The Importance of Getting the Temperature Right
Although it is not a precise measurement, experts state that if your nail has a red-hot glow, it is probably more than 1,000 degrees Fahrenheit! If it has a pale red glow, it is still in or around the 900-degree mark. If you add the CBD concentrate to a nail that is too hot, you will destroy many of the things that make CBD so amazing.
In reality, the optimal temperature for dabbing is between 300 and 400 degrees Fahrenheit, as this is the boiling point range for a lot of terpenes found in marijuana. For example, terpenes such as Linalool and Humulene have boiling points of 388 degrees, while a-Pinene has a boiling point of 311 degrees. (To be fair, this information is not relevant if you use CBD isolate, because isolates don’t have any terpenes).
If you have money to spend, you should invest in a dome-less nail or an e-nail. A dome-less nail is a metal piece that doesn’t require a glass dome to provide you with vapor. Rather, it contains numerous tiny holes that ensure the vapor goes straight through the piece.
While an e-nail is rather expensive, it is worth it if you’re serious about dabbing CBD. It allows you to not need a dome or a torch, which are pieces of equipment considered the most dangerous aspect of dabbing. Best of all, you can control the temperature of an e-nail which means you’re guaranteed to get the best from your CBD concentrate.
Quick Guide – CBD Dabs – How-To Instructions
Once the rig is set up and your dab is prepared on the dabber, you’re ready to get started. We advise you to sit while taking a dab, since the rush of THC can be physically intense.
Step 1: Turn on your torch and aim the flame directly at the nail. Most people will heat the nail until it begins turning red-hot. If you’re using an electronic nail, refer to the section below for more information on heating.
Step 2: Once the nail is hot, turn off your torch and place the glass dome over the nail. It’s recommended to let titanium nails cool for about 10 seconds and quartz nails about 45 seconds so the surface temperature isn’t too hot.
Step 3: Take your dabber, apply the dab directly on the nail inside the dome, and inhale slowly. Rotating the dabber tip on the nail can help you prevent wasting any oil stuck to the dabber.
Step 4: Exhale and enjoy!
Safety notice: nails and glass domes become extremely hot in the dabbing process. Take caution when handling them, and always wait for all pieces to cool down before you even think of touching them.
5 Benefits of Dabbing CBD
Experienced CBD users claim that no other consumption method can compare to dabbing. As long as you purchase premium grade CBD, you will find that the symptoms of conditions (such as nausea, anxiety, and chronic pain) will ease off in record time.
It is also a fact that dabbing pure CBD is a much more pleasant sensation that smoking cannabis, which can be testing on the lungs. Here is a quick look at just some of the benefits of dabbing CBD:
1) Antiemetic – Combats nausea, vomiting and motion sickness. This makes it helpful with the side effects from chemotherapy and opioid (heavy duty pain killers like hydrocodone, morphine, fentanyl and oxycodone these are listed as narcotics painkillers, as well as severe gastroenteritis. Why does this matter? The faster onset of a dab makes this a quick way to get that sick painful feeling to go away, so you can return to normal and functional.
2) Anticonvulsant – Fights against seizures and epilepsy, alone that is very impressive, but it is also being used for its antipsychotic properties. Antipsychotics help those with bipolar, and borderline personality disorder, by acting as a mood stabilizer. Anxiolytic, which means it also combats anxiety and panic, as well as being an antidepressant. Why does this matter? This is just a whole lot of great news for those that suffer from anxiety, social anxiety, panic attacks, clinical depression, bipolar depression, as well as those suffering from epilepsy and seizures.
3) Anti inflammatory – Reduces inflammation and swelling giving relief to many arthritis sufferers, as well as helping with chronic pain. Why is this important? In states with medicinal marijuana a significant number of deaths due to opioid overdose have lessened between 16 and 31 percent, as people switch to cannabis for their pain relief.
4) Antioxidant – Oxygen, the stuff we breathe in order to survive, is corrosive to the tissues of our bodies and causes cell degradation. We have all seen what happens to metal left unprotected from oxygen, it rusts. The best part is antioxidants prevent this cell degradation in our bodies by inhibiting oxidation of healthy cells. The release of free radicals can farther damage these cells.
5) Antitumor / Anti cancer – Prevents or combats the growth of cancerous and non cancerous tumors in the body. This is the big one causing so much fuss over marijuana in the U.S.. Why does this matter? In 2016, an estimated 1,685,210 new cases of cancer will be diagnosed and 595,690 people will die from the disease. Check out this article for more information on this.
Cons of Dabbing
Although there is a myriad of fantastic benefits associated with dabbing, there are a few perceived downsides too. There is a suggestion that dabbing is dangerous, but this only relates to the extraction methods that are used to produce the concentrate. It is not a wise move to try and extract CBD from hemp or cannabis because a combination of flammable gases and bad ventilation could result in an explosion. Also, there is no way of knowing how pure your end product is. You can eliminate this danger by purchasing a high-quality CBD isolate from a reputable company such as CBDistillery.
The next danger relates to the process itself. Again, it is a bad idea to create DIY dabbing equipment. A good quality nail and torch combo is essential as it enables you to dab safely without worrying about fires.
We also recommend taking it easy with dabbing if you are inexperienced. Although you won’t overdose on CBD, consuming an excessive amount could result in a very uncomfortable experience.
How Do I Measure the Dosage?
It takes time to get to grips with dosing levels if you’re an inexperienced dabber. For a start, most companies sell their concentrates in 0.5 grams, 1 gram, 3.5 gram and 7-gram sizes. High-quality concentrate is not cheap; you can expect to pay at least $30 per gram (or $25+ if you purchase a larger size).
We recommend searching for a product that clearly illustrates the level of CBD in it. For example, CBDistillery’s CBD slab contains 99.5% CBD, so you know there are 0.995 grams of cannabidiol per gram of product. Things are made a lot easier if you have a kitchen scale because you can accurately measure your dose. Most people begin with 10mg doses, but it can be tricky to measure out such a minute amount the first time out. However, practice makes perfect, and at least you know that the CBD you’re consuming is pure.
Final Thoughts on Dabbing CBD
If you have a medical condition and are fed up with worthless painkillers, save your money and purchase high-quality CBD and dabbing equipment instead. CBD is known to help the symptoms of a litany of medical conditions with no side effects. When you dab CBD, you can enjoy the purest form of this cannabinoid and benefit from rapid relief.
Enjoy the video guide below we found on youtube for those visual learners
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Newest CBD Discussions on Reddit
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Making Your own CBD E-juice or CBD Concentrate/Additive for Vaping
Making Your own CBD E-juice or CBD Concentrate/Additive for Vaping
About Vaping CBD: Vaporization is the fastest method of getting relief using CBD. Users tend to get relief using lower doses than other methods. Relief of symptoms may not last as long as other methods.
If you want to do a concentrate or vape additive to add to other e-juice, just skip the flavors, and use half the amount of PG base.
What do I need?
| Amount | Item | Cost |
|---|---|---|
| 1g | CBD Isolate | $25-$30 |
| 30ml | Propylene Glycol (PG) or Propanediol (PDO) | $10-$15 for 500ml |
| assorted | flavorings optional | <$10 |
| 1x | 30ml syringe w/ blunt needle | $4 |
| 1x | Miniature Funnel recommended | <$1 |
| 1x | 30ml Glass Dropper Bottle | $1.50 |
(What is PDO?)[https://www.reddit.com/r/CBD/comments/75hngm/guide_making_your_own_cbd_ejuice_for_vaping/dojw4wl/]
The flavors I used:
1 ,3 Propanediol (PDO) 250ml - diy-ejuice.com - $11.27
10ml Liquid Barn Sour - diy-ejuice.com - $3.44
10ml Cap Super Sweet - diy-ejuice.com - $3.44
15ml TFA Rainbow Drops - local shop - $3.95
Once you have your supplies purchased, everything but the CBD should last you many more doses of juice.
The Recipe
For more flavor recipes, see /r/diy_ejuice
Easy Sour Skittles – by rock513
| Flavoring | Percentage (PG) | Amount(PG) | Percentage (PDO) | Amount(PDO) |
|---|---|---|---|---|
| PG or PDO | 83% | 25ml | 70% | 20ml |
| TFA Rainbow Drops | 10% | 3ml | 15% | 5ml |
| LB Sour | 5% | 1.5ml | 12% | 3.5ml |
| Cappella Super Sweet | 1-2% | 0.5ml | 3% | 1-2ml |
The Guide (with Pictures)
Compared to Other Vape Juice:
| Brand | Name | CBD content | Price | Value per gram |
|---|---|---|---|---|
| Bluebird Botanicals | CBD Vape Oil 30ml | 1000mg | $74.95 | $75/g |
| Johnny Apple | Remedy CBD e-liquid 14ml | 140mg | $15 | $107/g |
| DIY | Homemade CBD vape juice 30ml | 1000mg | $55 | $55/g |
Note that not only is the DIY juice cheaper for the first bottle, but the price is limited only by how cheaply you can buy CBD isolate after your first batch.
More Discussion on DIY CBD vape juice
Newest /r/CBD reddit posts 5/1/2018
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How much CBD for Anxiety?
In 2015, the National Institute of Health allotted $21.2 million of its $111 million cannabinoid research budget towards projects exploring the medicinal potential of these compounds. These projects proposed to manipulate the body’s endocannabinoid system, either by modifying endocannabinoids or with phytocannabinoids from the cannabis plant.
While the primary psychoactive phytocannabinoid, delta 9-THC, has acknowledged medicinal value, cannabidiol (CBD) is widely known for its broad range of potential medicinal uses. In recognition of CBD’s vast potential, over $9 million in grants were awarded in 2015 to fund CBD-specific medicinal research.
Much of this research has centered around the treatment of epilepsy, with studies showing that CBD has significant potential for treating the condition in children at high doses. A daily dose over 600 mg reduced seizure frequency by 39%. While this is a far greater amount than you’d find in many of the CBD consumables available at your local dispensary, many retail CBD products with lower levels of the cannabinoid are reported to be effective at treating anxiety, pain, and a host of other disorders, either through self-experimentation or anecdotal reports.
So why not crank up the CBD dose to reduce your anxiety? If a little is good, shouldn’t a lot be better? It turns out that for CBD, the answer is no; CBD’s medicinal efficacy might require a particular dose range. Call it a “Goldilocks Zone,” where there’s not too much CBD but not too little, either.
Intriguingly, this Goldilocks Zone differs for each disorder. For instance, CBD appears to treat anxiety at relatively low doses compared to the high doses used to treat epilepsy.
While it may sound out of the ordinary, this “inverted-U” effect is actually quite common among drugs that affect multiple brain receptors, as CBD does. In fact, 37% of published toxicology articles report some degree of an inverted-U response, indicating that this is not a random event but instead reflects differential drug effects on brain targets.
The wide spectrum of CBD’s medical indications—it is used as a treatment for pain, anxiety, post-traumatic stress disorder, and other conditions—reflects its diverse set of brain and body targets. Since each of these many medical problems is impacted by CBD acting on specific receptors in the brain and body, differences in sensitivity for these targets may underlie CBD’s inverted U-response and define its Goldilocks Zone.
Renowned cannabinoid pharmacologist Roger Pertwee described CBD actions at low, medium, and high doses in an oft-cited review published in The British Journal of Pharmacology. As expected, low doses of CBD impact fewer neural targets than high doses. At relatively low doses, CBD can block endocannabinoids like anandamide and phytocannabinoids like delta 9-THC from interacting with receptors in the nervous system. This blocking action is thought to explain CBD’s ability to reduce the adverse effects that can accompany delta 9-THC exposure such as anxiety.
CBD’s anti-anxiety effects can also be attributed to its activation and enhancement of specific serotonin receptors. Serotonin is an important neurotransmitter involved in mood regulation and stress response; low serotonin levels are thought to contribute to conditions including generalized anxiety disorder and major depression. A common pharmacological treatment for these conditions involves enhancing the amount of serotonin available in an effort to activate the receptors using selective serotonin reuptake inhibitors, or SSRIs.
Rodent studies of CBD in anxiety and stress reveal that CBD similarly enhances serotonin receptor activation. In rats, a low-to-moderate dose of CBD has anti-anxiety effects following a stressful period of restraint (the rat equivalent of being placed in a straitjacket for an hour), but these anti-anxiety effects go away when the serotonin receptor 5-HT1a is blocked ahead of time. This suggests that low doses of CBD near the peak of the rodent’s inverted-U response reduce anxiety by activating 5-HT1a receptors.
Similar CBD doses in humans have been shown to be effective at reducing anxiety in individuals with generalized social anxiety disorder, and low to moderate doses are effective at reducing stress and improving performance in a simulated public speaking event. These positive effects are associated with a restoration of normal brain activity in key regions associated with anxiety and emotional dysregulation.
The positive effects of CBD in treating anxiety are experienced at about 25% of the dose used to treat epilepsy. That higher effective dose level reflects additional CBD brain targets beyond those active in treating anxiety.
While CBD activation of 5-HT1a receptors is insufficient to protect against seizures, a promising target for CBD’s antiepileptic effects is the receptor GPR55, which initiates a cascade of events that can have diverse effects in brain cells. CBD is an antagonist of GPR55, blocking its function and altering brain activity in a way that may protect against seizures. When administered in higher doses, though, the benefits of lower concentrations may be lost. Anti-anxiety effects, for instance, seem to be obstructed while higher concentrations of CBD work to block GPR55 receptors.
Identifying CBD’s many neural targets and their sensitivity is an exciting area of ongoing research. But knowing the optimal CBD dose for treating different conditions is a critical component of successful CBD treatment. The current research suggests that anxiety and depression-related disorders (e.g., obsessive compulsive disorder, autism, acute stress) respond best to low-moderate CBD doses, while epilepsy responds best to higher CBD doses.
Being able to titrate CBD dosing for specific disorders will lead to more efficacious CBD-centric therapies and reveal treatment strategies that may be able to combat multiple ailments at once. CBD’s Goldilocks Zone for treating anxiety illustrates the need for an improved understanding of the compound’s therapeutic mechanisms, while highlighting its vast treatment potential.
FAQ about CBD and where to find real medicine
Vetted Companies by /r/CBD
What is CBD
Cannabidiol—CBD—is a cannabis compound that has significant medical benefits, but does not make people feel “stoned” and can actually counteract the psychoactivity of THC.
The fact that CBD-rich cannabis is non-psychoactive or less psychoactive than THC-dominant strains makes it an appealing option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.
Scientific and clinical research—much of it sponsored by the US government—underscores CBD’s potential as a treatment for a wide range of conditions, including arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and other neurological disorders. CBD has demonstrable neuroprotective and neurogenic effects, and its anti-cancer properties are currently being investigated at several academic research centers in the United States and elsewhere. Further evidence suggests that CBD is safe even at high doses.
Dosage Threads
To search by dosage threads only
- Anxiety
- Crohn’s / UC / Digestive
- Cancer
- Epilepsy / Seizure
- Arthritis / AS
- PTSD
- Headaches / Migraines
FAQ
How does CBD work with (X) Medication?
- CBD has been shown in large quantities to interact with your CYP450, essentially “deactivating” it. This obviously being not good as it can cause adverse reactions with medications, especially anxiolytics. (Heighten/weaken strength, or activation of side effects like nausea, etc)
Does CBD Oil make you nauseous?
- People sometimes feel this way due to the carrier oil used, make sure you eat before taking it- You may be sensitive to the coconut oil or carrier oil.
What’s Full-spectrum vs Isolate?
- Full spectrum means the product contains THC and other cannabinoids, not just CBD. Isolate means it’s solely CBD, or the listed cannabinoid. (CBN, CBG, etc)
Will CBD make me positive on drug tests?
- See above. If Full-Spectrum it’s fully possible to test positive. If it’s isolate, it shouldn’t.
CBD with Keppra? Depakote? Diazepam? Clobazam? (Insert anticonvulsant here)
- Advise caution when mixing any anticonvulsant with CBD as it can pose risks as mentioned earlier with CYP450- Talk to your Neurologist/Epileptologist before committing. (Or ask Dr. Krishna!)
How does Omega-3 work with CBD?
- Essentially it’s said that Omega-3 deficiencies do have a correlation with low CB1 response, especially being that omega-3 deficiencies are a fairly common occurrence with the American diet. Low Omega-3 can lead to seasonal affect disorder- “Using mice, the study found that a deficiency in Omega-3 caused presynaptic CB1 receptors to uncouple from their effector G proteins, essentially disabling them. This dietary-induced impairment of CB1 function adversely affected emotional behavior.”, So essentially when Omega 3 is inplace its holding the CB receptors, preventing de-coupling. So with Omega-3 usage with CBD you are ensuring the CB receptors are not degraded, or decoupled, thus ensuring maximum potential benefit. There’s a good study about this and MDD here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533861/
How do I know if CBD is working?
- Typically CBD is shown as ‘working’ per symptomatic relief. It will not cure your ailments, merely treat symptoms- nausea, pain, anxiety, depression, etc. Compare yourself prior to taking it, and after. You should have relief from what you’re looking to address- if not, try a higher dosage.
Am I doing this right? I don’t feel the effect I thought I was going to feel?
- Due to CB1/CB2 cluster sizes, everyone experiences CBD slightly differently. If you’re expecting something like a THC high, or even alcohol inebriation- you’re not thinking about it right. Ideally, you will feel almost perfectly normal, just without the given symptom you’re looking to address. E.g. Pain > No Pain.
“What’s a good starting dose? I see studies using 300+ mg doses. I can’t afford that every day!”
- A starting dose would be 10-20mg daily. It is thought that CBD somewhat builds up in your body over the first week or so you are taking it, so the first few days you may not notice much of an effect. Once established, 30mg is considered a full daily dose for average people. Some with extreme pain or other ailments may up the dose to 50mg or more. If you need much more than 50-70mg daily then CBD may not be the best cost effective option for you. It seems that studies like the one you mention use large doses because, in all honesty, the effects of CBD with a daily dose are difficult to establish and empirically record. They use such large doses so that it exaggerates the effects for the study to actually see them. A commonly expressed view of the effects of CBD is simply that it makes you feel normal, it only really takes away symptoms and pain, instead of causing you to feel something. That is inherently difficult to observe in a scientific method, because it is subjective for each person. Hence why they use such a large dose.
Highest Rated /r/CBD
As most of you have found out by now – CBD is hit or miss depending on where it comes from. Many people have found there are a lot of snake oil sellers out there who are preying on the sick.
The Standard:
Each company reached out to us on their own, and then we presented them with a multi-page questionnaire about their process. These are not all the questions – we asked over 30 questions.
Some examples of questions are:
- Where do you source your CBD?
- What steps are taken to keep the medicine safe from degradation?
- Do you have all the permits required by state and county laws, to be in the cannabis industry? Please provide details.
- Can you provide passing test results for the following: Microbiological, Aerobic count, coliforms, enterobacteria, E coli count, yeast and mold, pseudomonas, salmonella, Pesticides/carbamates, Heavy metals, organophosphates and a cannabinoid potency test.
From their answers – our moderator team looked over each and every one. This gave us a good understanding of how their company works, and let us move on to the legal side of things.
The next steps were reviewing the documents sent over. We looked up each company, made sure they had all permits required by the state in order to operate. If they did, they moved on to the last step.
Each company that made it this far sent in samples of their products. These samples were tested by patients with different ailments. A few were sent to the moderator in Florida where two patients; 1. with Cerebral Palsy. 2. with mental health disorder – tested each product sent.
The other companies sent their product to the moderator team in California, where two patients 1. with M.S 2. Disabled w/ pain management – took the samples as well.
Both teams found the samples from the companies selected to be extremely high-quality products and HAD POSITIVE RESULTS on their ailments.
The following are those companies. (This list is not set in stone, companies can be added, or removed If you’re a company, please send a private message to ‘/r/CBD‘ and the mod team can look at your company.
The following are those companies. (This list is not set in stone, companies can be added, or removed If you’re a company, please send a private message to ‘/r/CBD‘ and the mod team can look at your company.
NuLeaf Naturals [COUPON CODE]: CBD10 10% OFF ENTIRE ORDER
A great company based out of Denver Colorado, their CBD products are top of the line. They are in line with all requirements listed above, but specifically, their product is superb.
BlueBird [COUPON CODE]: redditcbd25 25% OFF ENTIRE ORDER
One of the leaders in the CBD industry – Bluebird is known for quality. They are a huge supplier of CBD and often times supply some of the lower level CBD sellers. This company is always good. They provide testing for each batch, and their prices reflect the quality. They are a wide range of products from isolates to extracts to tinctures.
These are the official bluebird distributors for Europe! If your looking to get European CBD this is the place. Same exact product as bluebird, just for the EU.
Populum Coupon Code 10% OFF – LUVREDDIT10
A great company from texas that offers a product promised to be pure as can be. Their results for testing are nice, their product has great quality, and they uphold high morals. [Tincture](2m8pUS6)
Receptra Naturals Coupon Code 15% OFF – redditCBD
Colorado based company Receptra Naturals offers some of the best CBD products. With above standard testing done on each batch, the product is proven to be a pure as possible. Locally sourced from our family-owned farms in Colorado.
Lazarus Naturals Coupon Code 10% OFF – reddit10 One of the oldest and best CBD producers on the West Coast. They have every type of CBD product and even RSO oil.
Another great Colorado company. Their product speaks for itself and is highly effective. At the moment they have been having issues with credit card processors and can only take payment over the phone. But they still ship and deliver a great product.
One of the highest rated CBD vendors out of denver. Known for their slabs of crystal CBD isolate and great prices.
Vermont based hemp growers.
Palmetto Harmony [COUPON CODE]:redditcbd 10% OFF ENTIRE ORDER
High prices but great feedback from the other mods.
They are an industry leader for B2B CBD sales. Wholesaling and bulk. If you want to start a CBD company, source it from here. They are high quality and provide REAL medicine.
Video Series: Watch these 5 videos to become a CBD expert
Start with these five videos. these 5 videos go from easy to hard. If you finish them all, you’re probably a CBD expert at this point. Enjoy all five, they are all great videos! See how far you make it! If you finish them all, leave a comment sharing the coolest thing you learned.
[yotuwp type=”videos” id=”31SrjjgPbhU,qe6rKG_ca3w,20rGSogHkAk,1K-GMUFtRHs,xtphZejvGhk” ]
Basic Introduction to CBD
Everything you need to know about CBD oil
What is CBD oil?
CBD is one of many compounds, known as cannabinoids, that are found in the cannabis plant. Researchers have been looking at the potential therapeutic uses of CBD.
Oils that contain concentrations of CBD are known as CBD oils. The concentration and uses of different oils vary.
Is CBD marijuana?
Until recently, the most well-known compound in cannabis was delta-9 tetrahydrocannabinol (THC). This is the most active ingredient in marijuana.
Marijuana contains both THC and CBD, but the compounds have different effects.
THC is well-known for the mind-altering “high” it produces when broken down by heat and introduced into the body, such as when smoking the plant or cooking it into foods.
Unlike THC, CBD is not psychoactive. This means that it does not change the state of mind of the person who uses it. However, it does appear to produce significant changes in the body and has been found to have medical benefits.
Most of the CBD used medicinally is found in the least processed form of the cannabis plant, known as hemp.
Hemp and marijuana come from the same plant, cannabis sativa, but they are very different.
Over the years, marijuana farmers have selectively bred their plants to be very high in THC and other compounds that interested them, either for a smell or an effect they had on the plant’s flowers.
On the other hand, hemp farmers have not tended to modify the plant. It is these hemp plants that are used to create CBD oil.
How CBD works
All cannabinoids, including CBD, attach themselves to certain receptors in the body to produce their effects.
The human body produces certain cannabinoids on its own. It has two receptors for cannabinoids, called CB1 receptors and CB2 receptors.
CB1 receptors are found all around the body, but many of them are in the brain.
The CB1 receptors in the brain deal with coordination and movement, pain, emotions and mood, thinking, appetite, and memories, among others. THC attaches to these receptors.
CB2 receptors are more common in the immune system. They affect inflammation and pain.
It used to be thought that CBD acts on these CB2 receptors, but it appears now that CBD does not act on either receptor directly. Instead, it seems to influence the body to use more of its own cannabinoids.
Benefits
Because of the way that CBD acts in the body, it has many potential benefits.
Natural pain relief or anti-inflammatory properties
People commonly use prescription or over-the-counter drugs to relieve pain and stiffness, including chronic pain.
Some people feel that CBD offers a more natural way to lower pain. A study published in the Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats.
The researchers suggest that the non-psychoactive compounds in marijuana, such as CBD, could be a new treatment for chronic pain.
Quitting smoking and drug withdrawals
There is some promising evidence that CBD use may help people to quit smoking. A pilot study posted to Addictive Behaviors found that smokers who used an inhaler containing the compound CBD smoked fewer cigarettes but did not have any additional craving for nicotine.
Another similar study posted to Neurotherapeutics found that CBD may be a promising substance for people who abuse opioids.
Researchers noted that some symptoms experienced by patients with substance use disorders might be reduced by CBD. These include anxiety, mood symptoms, pain, and insomnia.
These are early findings, but they suggest that CBD may be used to avoid or reduce withdrawal symptoms.
Epilepsy and other mental health disorders
CBD is also being studied for its possible role in treating epilepsy and neuropsychiatric disorders.
A review posted to Epilepsia noted that CBD has anti-seizure properties and a low risk of side effects for people with epilepsy.
Studies into CBD’s effect on neurological disorders suggest that it may help to treat many of the disorders that are linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases.
Another study published in Current Pharmaceutical Design found that CBD may have similar effects to certain antipsychotic drugs and that it may be safe and effective in treating patients with schizophrenia.
More research is needed to understand how this works, however.
Helps fight cancer
CBD has been studied for its use as an anti-cancer agent.
A review posted to the British Journal of Clinical Pharmacology notes that CBD appears to block cancer cells from spreading around the body and invading an area entirely.
The review indicates that this compound tends to suppress the growth of cancer cells and promote the death of these cells.
Researchers note that CBD may help in cancer treatment because of its low toxicity levels. They call for it to be studied along with standard treatments, to check for synergistic effects.
Anxiety disorders
Patients with chronic anxiety are often advised to avoid cannabis, as THC can trigger or amplify anxiety and paranoia in some people.
However, a review from Neurotherapeutics suggests that CBD may help to reduce the anxiety felt by people with certain anxiety disorders.
The researchers point to studies showing that CBD may reduce anxiety behaviors in disorders such as:
- post-traumatic stress disorder
- general anxiety disorder
- panic disorder
- social anxiety disorder
- obsessive-compulsive disorder
The review notes that current medications for these disorders can lead to additional symptoms and side effects and that people may stop taking the drugs because of these unwanted effects.
CBD has not shown any adverse effects in these cases to date, and the researchers call for CBD to be studied as a potential treatment method.
Type 1 diabetes
Type 1 diabetes is caused by inflammation when the immune system attacks cells in the pancreas.
Recent research posted to Clinical Hemorheology and Microcirculation found that CBD may ease the inflammation in the pancreas in type 1 diabetes. This may be the first step in finding a CBD-based treatment for type 1 diabetes.
Acne
Acne treatment is another promising use for CBD. The condition is caused, in part, by inflammation and overworked sebaceous glands in the body.
A recent study posted to the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body.
CBD could be a future treatment for acne vulgaris, the most common form of acne.
Alzheimer’s disease
Initial research published in the Journal of Alzheimer’s Disease found that CBD was able to prevent the development of social recognition deficit in subjects.
This means that CBD could potentially prevent people in the early stages of Alzheimer’s from losing their ability to recognize the faces of people that they know. This is the first evidence that CBD has potential to prevent Alzheimer’s disease symptoms.
Legality
Cannabis is legal for either medicinal or recreational use in some but not all states. Other states approve CBD oil as a hemp product without approving the general use of medical marijuana.
Laws may differ between federal and state level, and current marijuana and CBD legislation in the United States can be confusing, even in states where marijuana is legal.
There is an ever-changing number of states that do not necessarily consider marijuana to be legal but have laws directly related to CBD oil. This information is up to date as of July 24, 2017, but the laws frequently change.
The laws vary, but they generally approve CBD oil as legal for treating a range of epileptic conditions at various concentrations. A full list of states that have CBD-specific laws is available here.
Different states also require different levels of prescription to possess and use CBD oil. In Missouri, for example, a person must show that three other treatment options have been unsuccessful in treating epilepsy.
If you are considering CBD oil as a treatment for a suitable condition, talk to your local healthcare provider. They will have an understanding of safe CBD sources and local laws surrounding usage. Research the laws for your own state. In most cases, a prescription will be required.
Side effects
Many small-scale studies have looked into the safety of CBD in adults and found that it is well tolerated across a wide range of doses.
There have been no significant side effects in the central nervous system or effects on vital signs and mood among people who use it either slightly or heavily.
The most common side effect noted is tiredness. Some people have noticed diarrhea and changes in appetite or weight.
Risks
There are still very little long-term safety data available, and, to date, tests have not been carried out on children.
As with any new or alternative treatment option, a patient should discuss CBD with a qualified healthcare practitioner before use.
The United States Food and Drug Administration (FDA) has not approved CBD for the treatment of any condition. It can be difficult to know whether a product contains a safe or effective level of CBD or whether the product has the properties and contents stated on its packaging and marketing.
How to use
CBD oil is used in different ways to relieve the symptoms of different conditions.
Some CBD oil products can be mixed into different foods or drinks, taken from a pipette or dropper, or are available as a thick paste to be massaged into the skin. CBD can also be purchased in capsule form.
Other products are provided as sprays that are meant to be administered under the tongue.
Here are a few recommended dosages, although these may vary between individuals based on other factors, such as body weight, the concentration of the product, and the condition being treated.
Due to the lack of FDA regulation for CBD products, seek advice from a medical professional before settling on any particular dosage.
All dosages relate to taking CBD oil by mouth. These can include:
- Chronic pain: Take between 2.5 and 20 milligrams (mg) by mouth for no more than 25 days.
- Epilepsy: Consume between 200 and 300 mg of CBD by mouth daily for up to 4.5 months.
- Movement problems associated with Huntington’s disease: Taking 10 mg every day for six weeks can help ease movements.
- Sleep disorders: Take between 40 and 160 mg.
- Schizophrenia: Consume between 40 and 1,280 mg CBD by mouth daily for up to 4 weeks.
- Glaucoma: One dose of between 20 and 40 mg applied under the tongue can help to relieve pressure in the eye. However, caution is advised – doses greater than 40 mg might actually increase pressure.
As regulation in the U.S. increases, more exact doses and prescriptions will start to emerge.
After discussing dosage and risks with a doctor, and researching regional legal use, it is important to compare different brands. There are a range of different CBD oils available to purchase online, with different benefits and applications.
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